ISSN: 2148-4902 | E-ISSN: 2536-4553
Northern Clinics of Istanbul Gastric Hepatoid Carcinoma: Report of A Case [North Clin Istanb]
North Clin Istanb. Ahead of Print: NCI-97720 | DOI: 10.14744/nci.2020.97720

Gastric Hepatoid Carcinoma: Report of A Case

Metin Leblebici1, Cem Ilgın Erol1, Özgür Ekinci1, Nesrin Gündüz2, Furkan Kilic1, Mehmet Acar1, Tunc Eren1, Rabia Burcin Girgin3, Orhan Alimoglu1
1Istanbul Medeniyet University, Department of General Surgery
2Istanbul Medeniyet University, Department of Radiology
3Istanbul Medeniyet University, Department of Pathology

Gastric Hepatoid Carcinoma (GHC) is a rare type of gatric cancer with a tendency to have poor prognosis and metastasize to the liver. GHCs generally show histopathologically hepatocellular differentiation and secrete Alpha Fetoprotein (AFP). AFP production can occur in cancers originating from the embryologically similar liver, gastrointestinal tract and yolk sac and often metastasizes to the liver. Although GHC is aggressive, it may not always cause liver metastasis and may invade into the other abdominal organs by direct contact. In this article, we present a case of locally advanced GHC with high AFP levels.

Keywords: Gastric cancer; AFP protein, human; Gastric diseases

Gastrik Hepatoid Karsinom: Olgu Sunumu

Metin Leblebici1, Cem Ilgın Erol1, Özgür Ekinci1, Nesrin Gündüz2, Furkan Kilic1, Mehmet Acar1, Tunc Eren1, Rabia Burcin Girgin3, Orhan Alimoglu1
1Istanbul Medeniyet University, Department of General Surgery
2Istanbul Medeniyet University, Department of Radiology
3Istanbul Medeniyet University, Department of Pathology

Gastric Hepatoid Carcinoma (GHC) is a rare type of gatric cancer with a tendency to have poor prognosis and metastasize to the liver. GHCs generally show histopathologically hepatocellular differentiation and secrete Alpha Fetoprotein (AFP). AFP production can occur in cancers originating from the embryologically similar liver, gastrointestinal tract and yolk sac and often metastasizes to the liver. Although GHC is aggressive, it may not always cause liver metastasis and may invade into the other abdominal organs by direct contact. In this article, we present a case of locally advanced GHC with high AFP levels. (NCI-2019-0339.R1)

Anahtar Kelimeler: Gastric cancer; AFP protein, human; Gastric diseases



Corresponding Author: Metin Leblebici
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